Product Name:
Cleaved-CASP3 p12 (D175) Polyclonal Antibody
Catalog No.:
E-AB-30003
Pack Size:
120uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1mg/mL. Affinity purified antibody.
Features:

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Host: Rabbit

Cleaved-CASP3 p12 (D175) Polyclonal Antibody.

Clonality: Polyclonal Antibody.

Antibody Isotype: IgG.

Conjugation: Unconjugated.

Concentration: 1mg/mL.

Immunogen: Synthesized peptide derived from the Internal region of human Caspase-3 p12.

Dilution: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.

Gene ID: 836.

Gene Accession no.

Swissprot No.P42574.

Research Areas:Cancer, Cell Biology, Metabolism, Neuroscience

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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