Product Name:
Cleaved-PARP1 (G215) Polyclonal Antibody
Catalog No.:
E-AB-30059
Pack Size:
120uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1mg/mL. Affinity purified antibody.
Features:

Reactivity: Human

Applications: WB, ELISA

Host: Rabbit

Cleaved-PARP1 (G215) Polyclonal Antibody.

Clonality: Polyclonal Antibody.

Antibody Isotype: IgG.

Conjugation: Unconjugated.

Concentration: 1mg/mL.

Immunogen: Synthesized peptide derived from the Internal region of human PARP-1.

Dilution: WB 1:500-1:2000, ELISA 1:5000

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.

Gene ID: 142.

Gene Accession no.

Swissprot No.P09874.

Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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