Labaid
Product Name:
AIM2 Polyclonal Antibody
Catalog No.:
E-AB-30449
Pack Size:
120uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1mg/mL. Affinity purified antibody.
Features:

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Host: Rabbit

AIM2 Polyclonal Antibody.

Clonality: Polyclonal Antibody.

Antibody Isotype: IgG.

Conjugation: Unconjugated.

Concentration: 1mg/mL.

Immunogen: Synthesized peptide derived from the Internal region of human AIM2.

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.

Gene ID: 9447.

Gene Accession no.

Swissprot No.O14862.

Research Areas:Cancer, Epigenetics and Nuclear Signaling

Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-©, AIM2 is thought to act as a tumor suppressor by repressing NF˚B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of å-helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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