AIRE Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1mg/mL.
Immunogen: Synthesized peptide derived from the Internal region of human AIRE-1.
Dilution: WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:10000
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.
Gene ID: 326.
Gene Accession no.
Swissprot No.O43918.
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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