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Product Name:
AMPK alpha1/2 Polyclonal Antibody
Catalog No.:
E-AB-30491
Pack Size:
120uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1mg/mL. Affinity purified antibody.
Features:
Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC-p, ELISA
Host: Rabbit
AMPK alpha1/2 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1mg/mL.
Immunogen: Synthesized peptide derived from human AMPKα1/2 around the non-phosphorylation site of Thr183/172..
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.
Gene ID: 5562/5563.
Gene Accession no.
Swissprot No.Q13131,P54646.
Research Areas:Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalyticalpha subunit and regulatorybeta andgamma subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul