Labaid
Product Name:
CASP10 B/C Polyclonal Antibody
Catalog No.:
E-AB-30753
Pack Size:
120uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1mg/mL. Affinity purified antibody.
Features:

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Host: Rabbit

CASP10 B/C Polyclonal Antibody.

Clonality: Polyclonal Antibody.

Antibody Isotype: IgG.

Conjugation: Unconjugated.

Concentration: 1mg/mL.

Immunogen: Synthesized peptide derived from the C-terminal region of human Caspase-10 B/C.

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.

Gene ID: 843.

Gene Accession no.

Swissprot No.Q92851-2,4.

Research Areas:Cancer, Cell Biology, Metabolism

Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-AMC and Asp-Glu-Val-Asp-AMC.Isoform C is proteolytically inactive. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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