CD88 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1mg/mL.
Immunogen: Synthesized peptide derived from human CD88 around the non-phosphorylation site of Ser338..
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.
Gene ID: 728.
Gene Accession no.
Swissprot No.P21730.
Research Areas:Cancer, Metabolism, Immunology, Signal transduction
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520). Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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