Product Name:
CYP2C19 Polyclonal Antibody
Catalog No.:
E-AB-31101
Pack Size:
120uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1mg/mL. Affinity purified antibody.
Features:

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Host: Rabbit

CYP2C19 Polyclonal Antibody.

Clonality: Polyclonal Antibody.

Antibody Isotype: IgG.

Conjugation: Unconjugated.

Concentration: 1mg/mL.

Immunogen: Synthesized peptide derived from the Internal region of human CYP2C19.

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.

Gene ID: 1557.

Gene Accession no.

Swissprot No.P33261.

Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.CYP2C19 (Cytochrome P450 Family 2 Subfamily C Member 19) is a Protein Coding gene. Diseases associated with CYP2C19 include Mephenytoin Poor Metabolizer and Cyp2c19-Related Altered Drug Metabolism. Among its related pathways are Cytochrome P450 - arranged by substrate type and Paroxetine Pathway, Pharmacokinetics. GO annotations related to this gene include enzyme binding and iron ion binding. An important paralog of this gene is CYP2C9. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul

Enquire Now