E2F1 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1mg/mL.
Immunogen: Synthesized peptide derived from human E2F-1 around the non-phosphorylation site of Thr433..
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.
Gene ID: 1869.
Gene Accession no.
Swissprot No.Q01094.
Research Areas:Cancer, Epigenetics and Nuclear Signaling
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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