IL6 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 0.8 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IL-6.
Dilution: WB 1:1000, IHC 1:500-1:800, IF 1:500-1:800
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P05231,P08505,P20607.
Research Areas:Cancer, Metabolism, Immunology, Neuroscience
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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