BBC3 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 2mg/mL.
Immunogen: Recombinant Human Bcl-2-binding component 3 protein.
Dilution: IHC 1:100-1:200
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Gene ID: 27113.
Gene Accession no.
Swissprot No.Q9BXH1.
Research Areas:Cancer, Cell Biology, Metabolism, Signal Transduction
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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