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Product Name:
HMGB1 Polyclonal Antibody
Catalog No.:
E-AB-70044
Pack Size:
200uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1.45 mg/mL. Affinity purified antibody.
Features:
Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF
Host: Rabbit
HMGB1 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1.45 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse HMGB1 .
Dilution: WB 1:1000, IHC 1:300-1:1000, IF 1:300-1:1000
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P09429,P63158,P63159.
Research Areas:Cancer, Epigenetics and Nuclear Signaling
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NF˚B family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul