MMP2 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 0.82 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse MMP2 .
Dilution: IHC 1:1000-1:2000
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P08253,P33436,P33434.
Research Areas:Cancer, Cell Biology, Cardiovascular, Metabolism
MMP2,also named as CLG4A,Gelatinase Am,TBE-1 and PEX,belongs to the peptidase M10A family. It is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature,angiogenesis,tissue repair,tumor invasion,inflammation,and atherosclerotic plaque rupture. MMP2 contributes to myocardial oxidative stress by regulating the activity of GSK3beta. It cleaves GSK3beta in vitro. MMP2 can be cleaved into PEX chain (~60kd).Western blot analysis showed that the 72 kDa and 62 kDa proteinase activities were pro-MMP2 and the active enzyme,respectively. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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