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Product Name:
IkB alpha Polyclonal Antibody
Catalog No.:
E-AB-70089
Pack Size:
200uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 1.3 mg/mL. Affinity purified antibody.
Features:
Reactivity: Human
Applications: IHC
Host: Rabbit
IkB alpha Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1.3 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IKBα.
Dilution: IHC 1:500-1:1000
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P25963,Q9Z1E3.
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,alpha (NFKBIA,synonyms: IKBA,MAD-3,NFKBI). NFKB1 or NFKB2 is bound to REL,RELA ,or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB),which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA,or IKBKB) marks them for destruction via the ubiquitination pathway,thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul
https://www.clementiabiotech.com/products/affinity-biosciences-14-3-3-eta-antibody-affinity-biosciences-df3492-100ul-200ul