AR Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 0.83 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor .
Dilution: IHC 1:500-1:1000
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P10275;P19091;P15207.
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Signal transduction
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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