Product Name:
ER beta Polyclonal Antibody
Catalog No.:
E-AB-70127
Pack Size:
200uL
Brand:
Elabscience Biotechnology Inc.
Product Detail:
Polyclonal Antibody, Isotype is IgG. Unconjugated type. Concentration: 500 ug/mL. Affinity purified antibody.
Features:

Reactivity: Mouse

Applications: IHC

Host: Rabbit

ER beta Polyclonal Antibody.

Clonality: Polyclonal Antibody.

Antibody Isotype: IgG.

Conjugation: Unconjugated.

Concentration: 500 ug/mL.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ESR2 .

Dilution: IHC 1:500-1:1000

Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.

Gene ID: .

Gene Accession no.

Swissprot No.O08537.

Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal transduction

Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors,which can transduce extracellular signals into transcriptional responses. It binds estrogens with an affinity similar to that of ESR1,and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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