AFP Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 0.9 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse AFP.
Dilution: WB 1:500-1:1000
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P02771,P02772.
Research Areas:Cancer, Cardiovascular, Developmental biology
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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