BAK1 Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1mg/mL.
Immunogen: Synthesized peptide derived from the N-terminal region of human Bak.
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4.
Gene ID: 578.
Gene Accession no.
Swissprot No.Q16611.
Research Areas:Cancer, Cell Biology
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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