LDLR Polyclonal Antibody.
Clonality: Polyclonal Antibody.
Antibody Isotype: IgG.
Conjugation: Unconjugated.
Concentration: 1 mg/mL.
Immunogen: KLH conjugated Synthetic peptide corresponding to LDL Receptor .
Dilution: IHC 1:200-1:1000
Buffer: PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Gene ID: .
Gene Accession no.
Swissprot No.P01130,P35951,P35952.
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE. Please contact our support expert at support@clementiabiotech.com for data sheet, manuals & quote.
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